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“Screening av PBDD/F i humana matriser”
Executive, Universitet, Örebro universitet, Örebro universitet, forskningscentrum människa teknik miljö, MTM.
Executive, Universitet, Örebro universitet, Örebro universitet, forskningscentrum människa teknik miljö, MTM.
Executive, Universitet, Örebro universitet, Örebro universitet, forskningscentrum människa teknik miljö, MTM.
Responsible organisation
2011 (Swedish)Report (Other academic)Alternative title
Screening of polybrominated dibenzo-p dioxins and furans(PBDD/Fs) in adipose tissue from the Swedish population (English)
Abstract [en]

In a screening study during 2007-2008, also performed by MTM and commissioned by

the Swedish EPA, the presence of polybrominated dibenzo-

p furans (PBDFs) were

detected in human adipose tissue from the Swedish population for the first time. In this

study ten additional adipose samples were analysed for polybrominated dibenzo-

p

dioxins and furans, PBDD/Fs. In all samples, 2,3,7,8-TeBDF was present in levels

ranging from 0.23 to 0.54 pg g

-1 lipid and pentabrominated furans were present in nine

out of ten samples. The levels of 2,3,7,8-TeBDF, 1,2,3,7,8- and 2,3,4,7,8-PeBDF were

similar to those reported in the previous screening study [1].

By lowering the detection limits by using larger injection volumes by employing the PTV

injection technique, 2,3,7,8-TeBDD, 1,2,3,4,7,8-/1,2,3,6,7,8-HxBDD, 1,2,3,4,6,7,8-

HpBDD, 1,2,3,4,7,8-HxBDF and 1,2,3,4,6,7,8-HpBDF were detected for the first time in

human adipose tissue samples from Sweden. 2,3,7,8-TeBDD was detected in five out of

ten samples in the range of 0.03-0.05 pg g

-1 lipid. 2,3,7,8-TeBDD has been detected in

samples with human origin earlier but not in samples from Sweden and levels of

1,2,3,4,7,8-HxBDF has previously been detected in human milk samples from several

countries, including Sweden. However, the detection of 1,2,3,4,7,8-/1,2,3,6,7,8-HxBDD,

1,2,3,4,6,7,8-HpBDD and 1,2,3,4,6,7,8-HpBDF in human tissue is to our knowledge

reported for the first time.

To summarize, results from nineteen samples (the present and previous study)

demonstrate the presence of brominated furans in the general Swedish population.

Additionally, the individuals having the highest PBDD/F concentrations had also the

highest levels of PCDD/Fs (pg TEQ g

-1). This might support the general assumption that

brominated and chlorinated dioxins have the same sources and exposure routes.

Place, publisher, year, edition, pages
2011. , 14 p.
National Category
Environmental Sciences
Research subject
Finance, National; Miljöövervakningens programområden, Toxic; Toxic, Screening; Environmental Objectives, A Non-Toxic Environment
Identifiers
URN: urn:nbn:se:naturvardsverket:diva-823OAI: oai:DiVA.org:naturvardsverket-823DiVA: diva2:711691
Available from: 2014-04-11 Created: 2014-04-11 Last updated: 2014-09-01Bibliographically approved

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