Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden - a 23 year long temporal trend study
Executive, Universitet, Karolinska institutet, Karolinska institutet, institutet för miljömedicin, IMM.
Executive, Myndigheter, Livsmedelsverket, SLV. Executive, Universitet, Swedish University of Agricultural Sciences.
Executive, Universitet, Swedish University of Agricultural Sciences.
Executive, Universitet, Karolinska institutet, Karolinska institutet, institutet för miljömedicin, IMM.
Show others and affiliations
Responsible organisation
2020 (English)Report (Other academic)
Abstract [en]

Exposure to methylmercury (MeHg) through fish is a global public health problem. Exposure monitoringis essential for health risk assessment, especially in pregnant women and children due to the documented neurotoxicity. Herein, we evaluate a time series of MeHg exposure via fish in primiparous Swedish women, covering a time period of 23 years (1996e2019). The 655 included mothers were part ofthe POPUP study (Persistent Organic Pollutants in Uppsala Primiparas) conducted by the Swedish FoodAgency (SFA). MeHg exposure was assessed via measurements of total mercury (Hg) in hair using either cold vapor atomic fluorescence spectrophotometry or inductively coupled plasma mass spectrometry, showing very good linear agreement (R2 ¼ 0.97). Maternal characteristics and fish consumption were obtained via questionnaires. The median concentration of total Hg in hair was 0.38 mg/kg (range 0.17e1.5) in 1996 and 0.25 mg/kg (range 0.03e1.1) in 2019. On average the women consumed 11 ± 8.2 mealsof fish per month, and fish consumption was positively correlated with total Hg in hair (Spearmancorrelation: 0.39; p < 0.001). In multiple regression analyses, the geometric mean annual decrease oftotal Hg in hair was 2.5% (95% CI: -3.2, 1.8%). Total fish consumption increased up to 2011 (B: 0.32times/month per year; 95% CI 0.17, 0.46) after which it started to decline (B: -0.66 times/month per year;95% CI -0.92, 0.40). Moreover, both total Hg in hair and fish consumption was positively associated withmaternal age and education, and inversely associated with pre-pregnancy BMI. In conclusion, theexposure to MeHg via fish appears to be slowly declining among Swedish pregnant women.

Place, publisher, year, edition, pages
Elsevier Ltd. , 2020. , p. 8
Keywords [en]
Methylmercury, Hair, Exposure assessment, Biomarker, ICPMS, Temporal trend
National Category
Environmental Sciences
Research subject
Finance, National; Miljöövervakning, Health; Environmental Objectives, A Non-Toxic Environment
Identifiers
URN: urn:nbn:se:naturvardsverket:diva-8758OAI: oai:DiVA.org:naturvardsverket-8758DiVA, id: diva2:1523256
Available from: 2021-01-27 Created: 2021-01-27 Last updated: 2021-01-27

Open Access in DiVA

fulltext(549 kB)154 downloads
File information
File name FULLTEXT01.pdfFile size 549 kBChecksum SHA-512
30fbd95d01ed45c2ddd2ca4bdd5d820c1e884d0f6f9855dd45c22973186820cb50c3236bd8ca072b94ac17b72d8faaa287851a79f35856827228d4f299d8b2ca
Type fulltextMimetype application/pdf

By organisation
Karolinska institutet, institutet för miljömedicin, IMMLivsmedelsverket, SLVSwedish University of Agricultural Sciences
Environmental Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 154 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 134 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf