The levels of five perfluoroalkylated (PFA) compounds, PFOS, PFOA, PFHxS, PFOSA and

PFNA were determined in whole blood and plasma from 47 males and 36 females

representing the Swedish population. The analytical method developed and used includes

solid-phase extraction and liquid chromatography electrospray masspectrometry. PFOS was

the PFA found at the highest concentration in whole blood (18.2 pg/ul) followed by PFOSA

(4.1 pg/μl), PFOA (2.7 pg/μl), PFHxS (2.3 pg/μl) and PFNA (0.3 pg/μl). Besides the five

compounds determined, we were able to detect PFHxA, PFDA, PFDS, PFUnDA, PFDoDA

and PFTDA in some of the samples/at low concentrations, the only compound included in this

study that we did not detect was PFBuS. This shows that the Swedish population are exposed

for a large number of PFAs. The concentrations of PFOS and PFOA correspond to those

found in USA. The correlation between PFOS and the other compounds was studied in order

to find out if there is a common source of exposure. Only a very week correlation between

PFOS and PFOA could be seen.